Here I detail the numerous mechanisms of action of chlorine dioxide in the human body which make it a viable treatment in a broad array of human illnesses.
Thank you, Dr. Kory, for this comprehensive synthesis of the multifaceted mechanisms of chlorine dioxide in human biology. I am especially grateful that you referenced our recent preclinical study on intra-tumoral chlorine dioxide injection therapy as part of the cancer-related applications. As a scientific inventor and long-time researcher in this field, I truly appreciate your commitment to building a rational, evidence-based understanding of this compound. Your work is helping elevate the conversation to a new level of scientific credibility.
I'm a paid subscriber (actually did so under 2 different emails by mistake, but can't figure out how to change it) and am having problems with the link in March 27 post 'The Numerous Mechanisms Of Action Of Chlorine Dioxide In Treating Human Illness'. The link comes up as a Private Link I can't get to - when code is sent for verification it then does not let me enter the code before flipping back to log in. Here is the sentence with the link - "Although in this post I am solely focusing on its mechanisms, I previously reviewed all aspects of the safety of therapeutic doses in this post." The link is "in this post". Any suggestions on how I can get to that previous post?
When considering chlorine dioxide therapy as an oxidative therapy, I recommend carefully addressing this viewpoint: "Oxidative therapies can also improve oxygen delivery to tissues by breaking down into oxygen (O₂)…"
ClO₂ is a selective oxidizing agent, and its mechanism of action is as follows:
- Directly oxidizing and reducing target molecules (e.g., sulfur- or iron-containing proteins) by transferring electrons.
- Being reduced into Cl⁻ or ClO₂⁻ itself without releasing molecular oxygen (O₂).
- Its antibacterial and anticancer mechanism is not "oxygen delivery," but rather disruption of the electronic structure, membrane stability, and metabolic chains of target molecules.
A good summary this, but there is no detail or discussion of the actual mechanism of ClO2. A typical chemistry perspective, I mean. Firstly, what happens to the chlorine atom, it doesn’t escape or react further as chlorine molecule, does it stay back as chloride ion ? Or does it also react with and degrade protein segments in cancerous cells or viruses ? As for the oxygen atom, I understand some of it becomes an oxygen molecule. But it would also be degrading protein segments in cancer cells, viruses etc, especially at susceptible sites with some of the amino acid units mentioned. Why is that it doesn’t degrade normal cellular matter or other functional/metabolic simple stand alone organic molecules present in the body. Many of them do have sites in their structures susceptible for oxidation. Even if we are talking about treatments generally involving very low concentrations of ClO2, if malignant sites are susceptible, so must be the normal cellular sites. Both carry the same basic organic structure templates.
Dr Kory thank you for all of your time, research, expertise. You have been instrumental since 2021 in turning my long covid around - Covid in 2020 with long covid and vaccine injured in 2021- formerly in healthcare so despite hesitation felt mandatory for my job- Tragic. (Happy news: aboutto go hike in the Grand Canyon!) You mentioned hyperbariac oxygen treatment in this post and curious what you or others think about an oxygen concentrator to replace hyperbariac chamber? (Hyperbariac just so expensive but I have found hyperbariac oxygen at 2 atmospheres really helpful not so much the softshell home version) Possibly answered my own question with that last comment. Keep up the amazing and much appreciated investigative work!
Thanks for your expert review of the literature on chlorine dioxide and chlorite's mechanism of action Dr. Kory. I will be posting about a new chlorine dioxide product soon that will also contain sodium chlorite, but at a much different proportion to chlorine dioxide than the MMS1 that people have generally been using for the last 15 or so years. In my opinion it has many advantages over MMS1, CDH (my first product) and CDS for most uses. Once it's out I would love to hear your thoughts on it. Take care
Worth sharing and reading!
Thank you Dr Kory for delving into this and for all of it. For all that you write for us. The highlight of my day.
Thank you, Dr. Kory, for this comprehensive synthesis of the multifaceted mechanisms of chlorine dioxide in human biology. I am especially grateful that you referenced our recent preclinical study on intra-tumoral chlorine dioxide injection therapy as part of the cancer-related applications. As a scientific inventor and long-time researcher in this field, I truly appreciate your commitment to building a rational, evidence-based understanding of this compound. Your work is helping elevate the conversation to a new level of scientific credibility.
https://www.biorxiv.org/content/10.1101/2023.11.24.568512v2
I'm a paid subscriber (actually did so under 2 different emails by mistake, but can't figure out how to change it) and am having problems with the link in March 27 post 'The Numerous Mechanisms Of Action Of Chlorine Dioxide In Treating Human Illness'. The link comes up as a Private Link I can't get to - when code is sent for verification it then does not let me enter the code before flipping back to log in. Here is the sentence with the link - "Although in this post I am solely focusing on its mechanisms, I previously reviewed all aspects of the safety of therapeutic doses in this post." The link is "in this post". Any suggestions on how I can get to that previous post?
How does chlorine dioxide affect the gut biome?
Andreas Kackler has a Substack article on this - essentially disrupting bad guys in
Dr Kory, since Dr Kevin still wagon told you the answer, and you decided to ignore and go back to "inflammation nonsense".
Then refused to simple to do the most important life saving interview ever.
Sadly that decision means.
The genocide will continue.
You chose poorly
You didn't have to join the gdi. You just had to do science.
Inflammation my ass.
Do you have any opinions on the exciting new research on adjunct therapies using dihydrogen monoxide?
Please review my explanation of the mechanism of chlorine dioxide: https://clo2xuewuliu.substack.com/p/the-magical-mechanism-of-chlorine
When considering chlorine dioxide therapy as an oxidative therapy, I recommend carefully addressing this viewpoint: "Oxidative therapies can also improve oxygen delivery to tissues by breaking down into oxygen (O₂)…"
ClO₂ is a selective oxidizing agent, and its mechanism of action is as follows:
- Directly oxidizing and reducing target molecules (e.g., sulfur- or iron-containing proteins) by transferring electrons.
- Being reduced into Cl⁻ or ClO₂⁻ itself without releasing molecular oxygen (O₂).
- Its antibacterial and anticancer mechanism is not "oxygen delivery," but rather disruption of the electronic structure, membrane stability, and metabolic chains of target molecules.
📌 Therefore: ClO₂ ≠ H₂O₂ ≠ O₃ ≠ O₂
Thanks. These clarifications are clear enough. Got to know more from your paper you had given link to below.
https://clo2xuewuliu.substack.com/p/comparison-of-chlorine-dioxide-hydrogen
A good summary this, but there is no detail or discussion of the actual mechanism of ClO2. A typical chemistry perspective, I mean. Firstly, what happens to the chlorine atom, it doesn’t escape or react further as chlorine molecule, does it stay back as chloride ion ? Or does it also react with and degrade protein segments in cancerous cells or viruses ? As for the oxygen atom, I understand some of it becomes an oxygen molecule. But it would also be degrading protein segments in cancer cells, viruses etc, especially at susceptible sites with some of the amino acid units mentioned. Why is that it doesn’t degrade normal cellular matter or other functional/metabolic simple stand alone organic molecules present in the body. Many of them do have sites in their structures susceptible for oxidation. Even if we are talking about treatments generally involving very low concentrations of ClO2, if malignant sites are susceptible, so must be the normal cellular sites. Both carry the same basic organic structure templates.
Dr Kory thank you for all of your time, research, expertise. You have been instrumental since 2021 in turning my long covid around - Covid in 2020 with long covid and vaccine injured in 2021- formerly in healthcare so despite hesitation felt mandatory for my job- Tragic. (Happy news: aboutto go hike in the Grand Canyon!) You mentioned hyperbariac oxygen treatment in this post and curious what you or others think about an oxygen concentrator to replace hyperbariac chamber? (Hyperbariac just so expensive but I have found hyperbariac oxygen at 2 atmospheres really helpful not so much the softshell home version) Possibly answered my own question with that last comment. Keep up the amazing and much appreciated investigative work!
Thanks for your expert review of the literature on chlorine dioxide and chlorite's mechanism of action Dr. Kory. I will be posting about a new chlorine dioxide product soon that will also contain sodium chlorite, but at a much different proportion to chlorine dioxide than the MMS1 that people have generally been using for the last 15 or so years. In my opinion it has many advantages over MMS1, CDH (my first product) and CDS for most uses. Once it's out I would love to hear your thoughts on it. Take care
looking forward to it - let me know