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Paxlovid is a combination of two drugs...one of which has a FDA black box warning.

"The Paxlovid drug label comes with the following Black Box Warning: Paxlovid includes ritonavir, a strong CYP3A inhibitor, which may lead to greater exposure of certain concomitant medications, resulting in potentially severe, life-threatening, or fatal events. Prior to prescribing Paxlovid: 1) Review all medications taken by the patient to assess potential drug-drug interactions with a strong CYP3A inhibitor like Paxlovid and 2) Determine if concomitant medications require a dose adjustment, interruption, and/or additional monitoring. Consider the benefit of Paxlovid treatment in reducing hospitalization and death, and whether the risk of potential drug:drug interactions for an individual patient can be appropriately managed."

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